4. Nesil EIA (Combine, Combo, DUO, HIV Ab/Ag) HIV-1’e özgül p24 antijeni ve HIV1/2’ye özgül antikorları birlikte inceleyen bir testtir. p24 yalnızca birkaç hafta boyunca kanda bulunabilir. Antikor testi 3. Nesil testlerle aynı pencere dönemine sahiptir.Bazı uzmanlar tarafından 6. haftada yapılan testler kesin olarak kabul edilse de resmi rehberler kesinlik için 12 haftada tekrar testi önermektedir.
AIDS Vancouver Helpline/Online helpline.aidsvancouver.org Private & Confidential 4th Generation EIA Blood test that looks for antibodies AND p24 protein antigens. Commonly referred to as the "combination," "combo" or "DUO" test. P24 protein is detectable immediately after infection but only for the first few weeks. The antibody (ab) test has a window period of 4-12 weeks post exposure. This test is widely available in North America. Most HIV specialists consider this test to be conclusive at 6 weeks but official HIV testing guidelines still recommend re-testing at 12 weeks for conclusive results. Conclusive at 3 months post exposure.